Faculty Opinions recommendation of Interactions between natural selection, recombination and gene density in the genes of Drosophila.
- 13 March 2002
- dataset
- Published by H1 Connect
- Vol. 160 (2) , 595-608
- https://doi.org/10.3410/f.1004873.56354
Abstract
This paper tests predictions from theoretical work suggesting that codon usage bias should be poorly maintained in genome regions where recombination is infrequent, taking into account the effects of the confounding factors of GC content and gene density. Based on a large number of Drosophila genes, both codon bias and gene expression are highest for those genes in regions with intermediate gene density.Keywords
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