Characterization of a Calcium‐Binding IgG Myeloma Protein
- 29 June 1974
- journal article
- Published by Wiley in Scandinavian Journal of Immunology
- Vol. 3 (3) , 277-285
- https://doi.org/10.1111/j.1365-3083.1974.tb01258.x
Abstract
A calcium‐binding IgG myeloma protein (A. L.) has previously been described It has now been characterized as an IgG1 lambda protein with two independent binding sites for calcium ions. The sites are localized in the Fab regions. Isolated heavy chains showed no unequivocal binding activity, whereas the light chains were active. The apparent intrinsic association constant for protein A.L., as found by equilibrium dialysis, was 104 l/mol.Keywords
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