CLINICAL STUDIES OF THE BLOOD VOLUME. II. THE RELATION OF PLASMA AND TOTAL BLOOD VOLUME TO VENOUS PRESSURE, BLOOD VELOCITY RATE, PHYSICAL MEASUREMENTS, AGE AND SEX IN NINETY NORMAL HUMANS

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Abstract
Plasma and total blood vol., venous pressure and blood velocity rates were detd. in 49 normal [male][male] and 41 normal [female][female] No relationship exists in normal persons between variations in total blood vol., venous pressure and blood velocity rate. The total blood vol. of normal [male][male] is greater than that of [feale][female], the difference being due to the greater red cell vol. of [male][male]. The absolute red cell vol. of [female][female] is less than that of [male][male] by a much greater degree than indicated by differences in red cell counts and hematocrit values. With increasing age there is a decline in the blood vol. comparable to decreases in basal metabolic rates and vital capacities. In comparison to average values, the absolute total blood vol. is high in muscular and obese persons, and low in thin individuals; the vol. per unit of body wt. is high in muscular and in thin individuals and low in obese persons. The blood vol. of normal individuals varies within wide limits. The relationship to height or surface area offers a useful basis for estimation of normal volume in clinical investigation.