A complex familial translocation involving chromosomes 5, 9 and 13

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Abstract
The chromosomes of two phenotypically normal individuals of a family with a complex chromosome rearrangement were studied. Karyotype analysis and measurements of certain chromosomes showed three abnormal chromosomes, and the apparently balanced karyotypes were interpreted as the result of reciprocal translocations between a B-, a C- and a D-group chromosome. The B- and D-group chromosomes involved were identified as a No. 5 and a No. 13 by means of autoradiography and the C-group chromosome as a No. 9 on morphological grounds.

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