The Immunological Release of Slow-Reacting Substance of Anaphylaxis from Bovine Lung

1 December 1974

journal article
Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology

Vol. 52 (6) , 1201-1204
https://doi.org/10.1139/y74-156

Abstract

Slow-reacting substance of anaphylaxis (SRS-A) was released immunologically from bovine lung in vitro. Polyphloretin phosphate inhibited release of SRS-A. Pretreatment of calves with aspirin potentiated SRS-A release on challenge. The partially purified SRS-A extract contracted the guinea-pig ileum and bovine pulmonary vein.

Keywords

ANAPHYLAXIS
ILEUM
VEIN
GUINEA
CALVES
SLOW REACTING
PARTIALLY
CONTRACTED
RELEASED IMMUNOLOGICALLY