Advanced Prostatic Carcinoma

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Abstract
FOURTEEN years have now elapsed since Huggins and his co-workers1 , 2 reported on the treatment of prostatic carcinoma by antiandrogenic methods. Although it has become apparent that orchiectomy or estrogenic hormones or both have failed to cure the disease, it is generally agreed that life is prolonged, pain and suffering are relieved, and the size and consistence of the prostatic neoplasm and often its distant lymphatic, osseous or pulmonic metastases are remarkably influenced in a sufficiently significant percentage of cases to warrant the institution of this treatment in all cases of "advanced" prostatic carcinoma.3 Certainly, for "early" prostatic carcinoma, an attempt . . .