Cortically Induced Inhibition of Neurons of Rat Substantia Nigra (Pars Compacta)

Abstract
The effects of electrical stimulation of prefrontal cortex upon neurons of substantia nigra (pars compacta) in anesthetized rats were mostly inhibition without antidromic excitation. Study of nigral neurons in which the inhibition from cadate-putamen was antagonized by iontophoretic bicuculline, showed that in only half of them the same drug also antagonized inhibition from the prefrontal cortex.