CHIMPANZEE ANTIBODIES TO PURIFIED HUMAN Ia-LIKE B CELL ANTIGENS12

Abstract
Chimpanzees were immunized with affinity-purified Ia-like antigens isolated from deoxycholate-solubilized membranes of HLA-DR homozygous human B lymphoblastoid cell lines. Three sera were produced, 2 monospecific for HLA-DR2 and HLA-DR7, respectively, and 1 containing antibodies to 2 specificities, HLA-DR3 and MT2.

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