Investigations on General Immune Reactivity in Untreated Cervical Cancer Patients

Abstract
Patients (74) with untreated cervical cancer (FIGO II and III) were skin tested with a battery of recall antigens, and also sensitized and challenged with DNCB [dinitrochlorobenzene]. A significant reduction of reaction to tuberculin, Varidase and DNCB was found in patients with stage III in comparison to healthy females of the same age group. Significant changes in immunoglobulin [Ig] levels, increase of IgA and decrease of IgG were observed in the cancer patients. Serum lysozyme values were the same as in the control group.