Enzymatic conversion of cephamycin C by D-amino acid oxidase from Trigonopsis variabilis.
- 1 January 1980
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 33 (6) , 585-590
- https://doi.org/10.7164/antibiotics.33.585
Abstract
D-Amino acid oxidase (EC 1.4.3.3) systems from T. variabilis SANK 59963 catalyze cephamycin C. The reaction products were assigned to 7.beta.-(5-carboxy-5-oxovalerylamido)-7.alpha.-methoxy-3-carbamoyl-3-cephem-4-carboxylic acid and 7.beta.-(4-carboxy-butyrylamido)-7.alpha.-methoxy-3-carbamoyl-3-cephem-4-carboxylic acid, respectively. D-Amino acid oxidase from hog kidney was not able to catalyze cephamycin C.This publication has 3 references indexed in Scilit:
- Purification and properties of beta-lactamase from Proteus morganiiJournal of Bacteriology, 1977
- Transaminase and D-Amino Acid Oxidase of Trigonopsis variabilisJournal of General Microbiology, 1962
- The structure of cephalosporin CBiochemical Journal, 1961