Effects of Neuraminidase Treatment on Solubilized Insulin Receptor
- 1 October 1980
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 12 (10) , 494-496
- https://doi.org/10.1055/s-2007-999185
Abstract
Neuraminidase treatment of triton-solubilized insulin receptors from rat fat cell membranes caused release of sialic acid and changed the isoelectric point (pI) of the insulin receptor from 4.7 to 5.6. Neuraminidase had no effect on the number or affinity of insulin receptors. The insulin receptor contains sialic acid, but this sialic acid apparently is not involved in the binding reaction.This publication has 0 references indexed in Scilit: