Nursing Home Residents andEnterobacteriaceaeResistant to Third-Generation Cephalosporins
Open Access
- 1 June 2004
- journal article
- research article
- Published by Centers for Disease Control and Prevention (CDC) in Emerging Infectious Diseases
- Vol. 10 (6) , 1050-1055
- https://doi.org/10.3201/eid1006.030662
Abstract
Limited data identify the risk factors for infection with Enterobacteriaceae resistant to third-generation cephalosporins among residents of long-term-care facilities. Using a nested case-control study design, nursing home residents with clinical isolates of Enterobacteriaceae resistant to third-generation cephalosporins were compared to residents with isolates of Enterobacteriaceae susceptible to third-generation cephalosporins. Data were collected on antimicrobial drug exposure 10 weeks before detection of the isolates, facility-level demographics, hygiene facilities, and staffing levels. Logistic regression models were built to adjust for confounding variables. Twenty-seven case-residents were identified and compared to 85 controls. Exposure to any cephalosporin (adjusted odds ratio [OR] 4.0, 95% confidence interval [CI] 1.2 to13.6) and log percentage of residents using gastrostomy tubes within the nursing home (adjusted OR 3.9, 95% CI 1.3 to 12.0) were associated with having a clinical isolate resistant to third-generation cephalosporins.Keywords
This publication has 29 references indexed in Scilit:
- Factores de riesgo asociados a infecciones por Klebsiella pneumoniae resistentes a ceftacidimaEnfermedades Infecciosas y Microbiología Clínica, 2003
- Risk factors in the acquisition of extended-spectrum β-lactamase Klebsiella pneumoniae: a case–control study in a district teaching hospital in TaiwanJournal of Hospital Infection, 2003
- Editorial Commentary: Looking for Risk Factors for the Acquisition of Antibiotic Resistance: A 21st‐Century ApproachClinical Infectious Diseases, 2002
- Extended-Spectrum β-Lactamase–ProducingEscherichia coliandKlebsiellaSpecies: Risk Factors for Colonization and Impact of Antimicrobial Formulary Interventions on Colonization PrevalenceInfection Control & Hospital Epidemiology, 2002
- Risk Factors for Emergence of Resistance to Broad-Spectrum Cephalosporins among Enterobacter sppAntimicrobial Agents and Chemotherapy, 2001
- Measuring and Interpreting Associations between Antibiotic Use and Penicillin Resistance in Streptococcus pneumoniaeClinical Infectious Diseases, 2001
- Multiple Antibiotic–Resistant Bacteria in Long‐Term‐Care Facilities: An Emerging Problem in the Practice of Infectious DiseasesClinical Infectious Diseases, 2000
- Multiply Antibiotic Resistant Gram-Negative Bacilli in a Long Term Care Facility A Case Control Study of Patient rick Factors and Prior Antibiotic UseInfection Control & Hospital Epidemiology, 1997
- Nursing Home DilemmasInfection Control & Hospital Epidemiology, 1997
- Gastrostomy tube infections in a community hospitalAmerican Journal of Infection Control, 1996