Effects of Fluoride in Remineralized Human Surface Enamel on Dissolution Resistance

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Abstract
Remineralized surfaces of human tooth enamel were dissolved at constant rates in 10 mM acetic acid at pH 4.0, and in 10 mM EDTA at pH 7.4 in a system that prevented redistribution of dissolved F. Surfaces remineralized 25 hours in 0.4 mM NaF (8 ppm F -) dissolved slower in acid or in EDTA than those remineralized in the absence of F-. The F- in three-hour remineralized surfaces had no effect on rates of mineral dissolution. Resistance to EDTA, as well as acid of 25-hour remineralized surfaces, indicates the occurrence of a maturation process, which may involve F- exchange for OH- ions in newly formed crystals. The results indicated that F- may slow caries by its action on remineralization if given sufficient time for this maturation.

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