Evidence for the stability and cytochrome P450 specificity of the phenobarbital-induced reductive halothane-cytochrome P450 complex formed in rat hepatic microsomes
- 1 June 1991
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 41 (11) , 1691-1699
- https://doi.org/10.1016/0006-2952(91)90171-z
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- Reductive metabolism of halothane by purified cytochrome P-450Biochemical Pharmacology, 1988
- Modulation of the reductive metabolism of halothane by microsomal cytochrome b5 in rat liverBiochimica et Biophysica Acta (BBA) - General Subjects, 1987
- Formation of a ferric carbanion complex from halothane and cytochrome P-450: electron spin resonance, electronic spectra, and model complexesBiochemistry, 1984
- Reductive halothane metabolite formation and halothane binding in rat hepatic microsomesChemico-Biological Interactions, 1984
- Halothane Hepatotoxicity: Relation Between Metabolic Activation, Hypoxia, Covalent Binding, Lipid Peroxidation and Liver Cell DamageHepatology, 1983
- Cytochrome P-450 and halothane metabolism. Decrease in rat liver microsomal P-450 in vitroChemico-Biological Interactions, 1983
- Suicidal inactivation of microsomal cytochrome P-450 by halothane under hypoxic conditionsBiochemical and Biophysical Research Communications, 1982
- The mechanism of reductive dehalogenation of halothane by liver cytochrome P450Biochemical Pharmacology, 1982
- Hepatotoxicity and Halothane Metabolism in an Animal Model with Application for Human ToxicityAnaesthesia and Intensive Care, 1979
- The mechanism of halothane binding to microsomal cytochrome P450Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1974