Effects of Repeated Ingestion of Large Quantities of Acetylsalicylic Acid on Membranous Bone Growth and Dentin Apposition in Young Monkeys

Publisher Website
Google Scholar
Abstract
Four oral doses of acetylsalicylic acid at 325 mg/kg body weight were given to young monkeys that received a series of injections of lead acetate as an intravital stain. Bone growth, including remodeling of the Haversian canal system, was greatly inhibited, whereas dentin apposition was unaffected.