Limited Sequence Divergence of HTLV-I of Indian HAM/TSP Patients from a Prototype Japanese Isolate
- 1 June 1993
- journal article
- case report
- Published by Mary Ann Liebert Inc in AIDS Research and Human Retroviruses
- Vol. 9 (6) , 495-498
- https://doi.org/10.1089/aid.1993.9.495
Abstract
Nucleotide sequences of two HTLV-I proviruses isolated from Indian patients with HAM/TSP were analyzed. The sequence data of the env, pX, and LTR regions showed 98-99% homologies with the prototype HTLV-I, ATK-1, isolated from a Japanese ATL patient, indicating that HTLV-I isolates in India and Japan are similar, with minor variations. However, certain small sequences of noncoding regions in the pX and LTR showed differences of 6.1 and 7.2%, respectively, thus the conclusion could vary depending on the regions and length of the s0equences used for comparison.Keywords
This publication has 20 references indexed in Scilit:
- LTR sequence and phylogenetic analyses of a newly discovered variant of HTLV-I isolated from the Hagahai of Papua New GuineaVirology, 1992
- Limited sequence variation in human T-lymphotropic virus type 1 isolates from North American and African patientsVirology, 1991
- Retrovirus From Human T-Cell Leukemia Virus Type I-Associated Myelopathy Is the Same Strain as a Prototype Human T-Cell Leukemia Virus Type IArchives of Neurology, 1990
- HTLV-I AND NEUROLOGICAL DISEASE IN SOUTH INDIAThe Lancet, 1989
- Molecular Cloning and Complete Nucleotide Sequence of an Adult T Cell Leukaemia Virus/Human T Cell Leukaemia Virus Type I (ATLV/HTLV-I) Isolate of Caribbean Origin: Relationship to Other Members of the ATLV/HTLV-I SubgroupJournal of General Virology, 1988
- Chronic progressive myelopathy associated with elevated antibodies to human T‐lymphotropic virus type I and adult T‐cell leukemialike cellsAnnals of Neurology, 1987
- ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESISPublished by Elsevier ,1985
- HTLV type I (U. S. isolate) and ATLV (Japanese isolate) are the same species of human retrovirusVirology, 1984
- Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease.Proceedings of the National Academy of Sciences, 1982
- Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphomaProceedings of the National Academy of Sciences, 1980