The quantity of rhodopsin in young human eyes
- 1 January 1991
- journal article
- research article
- Published by Taylor & Francis in Current Eye Research
- Vol. 10 (10) , 977-982
- https://doi.org/10.3109/02713689109020334
Abstract
The rhodopsin content of 20 eyes of infants and children ages 27 weeks gestation to 8 years (11 donors) was assayed and compared to the rhodopsin content of adults (36 eyes; 19 donors). Infants have significantly lower rhodopsin contents than adults. On average the rhodopsin content of young infants is about a third of adults. Previously reported full-field b-wave sensitivity of young infants is about 0.5 log units, that is about a third, less than adults. Thus, as previously found in infant rats, photon capture by rhodopsin appears to limit the dark adapted sensitivity of young human infants.Keywords
This publication has 11 references indexed in Scilit:
- Electroretinographic assessment of background adaptation in 10-week-old human infantsVision Research, 1991
- Development of the light response in neonatal mammalian rodsNature, 1991
- Predisposing factors to light-induced photoreceptor cell damage: Retinal changes in maturing ratsExperimental Eye Research, 1990
- The quantity of rhodopsin in human eyesCurrent Eye Research, 1990
- “Self-screening” of rhodopsin in rod outer segmentsVision Research, 1987
- The relationship of retinal sensitivity and rhodopsin in human infantsVision Research, 1986
- Rhodopsin, 11-cis vitamin A, and interstitial retinol-binding protein (IRBP) during retinal development in normal and rd mutant miceDevelopmental Biology, 1986
- KINETICS OF ROD OUTER SEGMENT RENEWAL IN THE DEVELOPING MOUSE RETINAThe Journal of cell biology, 1973
- INHERITED RETINAL DYSTROPHY IN THE RATThe Journal of cell biology, 1962
- The rhodopsin cycle in the developing vertebrate retina: I. Relation of rhodopsin content, electroretinogram and rod structure in the ratExperimental Eye Research, 1961