Immunological disturbance in West and Lennox-Gastaut syndromes
Open Access
- 1 June 1984
- journal article
- Published by FapUNIFESP (SciELO) in Arquivos de Neuro-Psiquiatria
- Vol. 42 (2) , 132-139
- https://doi.org/10.1590/s0004-282x1984000200005
Abstract
Cell-mediated and humoral immunity were investigated in 18 patients with West syndrome, 12 with Lennox-Gastaut syndrome and 19 healthy controls. The study included determination of Ô and  peripheral blood lymphocytes, serum levels of IgG, IgA and IgM, skin sensibilization with DNCB, intracutaneous PHA, leucocyte migration inhibition test and lymphocyte blastic transformation in the presence of PHA. Cell-mediated deficiency was detected in 28 children whereas low levels of immunoglobulins were observed only in 6 children. Immunological disturbances were more prominent in children with West syndrome.Keywords
This publication has 17 references indexed in Scilit:
- Cell-mediated and humoral immunity in west syndromeArquivos de Neuro-Psiquiatria, 1981
- IgA DEFICIENCY, EPILEPSY, AND HYDANTOIN MEDICATIONThe Lancet, 1976
- Primary Immunodeficiency with early Encephalopathy in Two SiblingsEuropean Neurology, 1975
- Cell-mediated immunity in leprosy and transfer of delayed hypersensitivity reactionsJournal of Allergy and Clinical Immunology, 1974
- Effect of phytohaemagglutinin in the leucocyte migration inhibition test as a measure of cell-mediated immunityJournal of Clinical Pathology, 1974
- Phytohemagglutinin (PHA) skin test in the diagnosis of cellular immunodeficiencyJournal of Allergy and Clinical Immunology, 1973
- Phytohemagglutinin skin test: A possible in vivo measure of cell-mediated immunityThe Journal of Pediatrics, 1972
- Immunological Abnormalities and HydantoinsBMJ, 1972
- Prognostic Implications of Electroencephalographic Findings of Hypsarrhythmia in First Year of LifeBMJ, 1971
- Immunochemical quantitation of antigens by single radial immunodiffusionImmunochemistry, 1965