Physiological regulation of blood pressure and kidney function by guanylyl cyclase isoforms
- 1 January 1997
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Nephrology and Hypertension
- Vol. 6 (1) , 58-63
- https://doi.org/10.1097/00041552-199701000-00011
Abstract
Guanylyl cyclase isoforms can serve as receptors for various molecules including atrial natriuretic peptide, brain natriuretic peptide, C-type natriuretic peptide and nitric oxide. It has been speculated these signaling pathways are important regulators of cardiovascular and renal physiology. Within the past year, gene targeting in particular has strengthened this speculation, suggesting critical roles of guanylyl cyclase receptors in both the chronic and acute regulation of blood pressure.Keywords
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