A Moving Story
- 22 February 2002
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 295 (5559) , 1480-1481
- https://doi.org/10.1126/science.1069823
Abstract
Many protein structures are known with high accuracy, but much less is known about their dynamics. In his Perspective, Falke highlights the report by Eisenmesser et al., who have used a nuclear magnetic resonance approach to follow protein transition state movements during catalysis in the enzyme cyclophilin A. The method should generate a wealth of new information about motions in working enzymes.Keywords
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