Chemistry and antiinflammatory activities of prodolic acid and related 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-alkanoic acids. 1
- 1 February 1975
- journal article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 18 (2) , 189-191
- https://doi.org/10.1021/jm00236a017
Abstract
The synthesis and antiinflammatory activities of a series of 23 novel 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-alkanoic acids are described and some relationships between structure and activity are discussed. One of these compounds, 1,3,4,9-tetrahydro-1-propylpyrano[3,4-b]indole-1-acetic acid (prodolic acid, USAN), has been selected for further studies.Keywords
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