High Resolution Images of Cell Surface Using a Tapping-Mode Atomic Force Microscope
- 1 November 1993
- journal article
- Published by IOP Publishing in Japanese Journal of Applied Physics
- Vol. 32 (11B) , L1711
- https://doi.org/10.1143/jjap.32.l1711
Abstract
We succeeded in obtaining high-resolution images of a cell surface using a tapping-mode atomic force microscope (tapping-mode AFM) in air. The resulting images resolved many particles of 40-80 nm in radius and distinguished regions where the particles formed clusters from other regions. Such images could not be obtained using a contact-mode atomic force microscope (contact-mode AFM) operated under the same conditions. The result demonstrates the possibility of cell surface research using the tapping-mode AFM with molecular resolution.Keywords
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