The biology of photodynamic therapy
- 1 May 1997
- journal article
- review article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 42 (5) , 913-935
- https://doi.org/10.1088/0031-9155/42/5/012
Abstract
The subcellular, cellular and tissue/tumour interactions with non-toxic photosensitizing chemicals plus non-thermal visible light (photodynamic therapy (PDT)) are reviewed. The extent to which endothelium/vasculature is the primary target is discussed, and the biochemical opportunities for manipulating outcome highlighted. The nature of tumour destruction by PDT lends itself to imaging outcome by MRI and PET.Keywords
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