Ultrastructural Effects of in Vitro Experimentation on Right Ventricular Papillary Muscle from Cats in Hypovolemic Shock

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Abstract
The present data demonstrate for the first time that repeated stimulation (2-3 hr in an oxygenated perfusate) of right ventricular papillary muscles from cats subjected to hypovolemic shock does not alter the ultrastructure of the shock lesions. Neither does the in vitro experimentation cause functional impairment as determined by the measured isometric twitch tension. The data also indicate that electron microscopy is important to the evaluation of papillary muscles from cats subjected to shock.