Numerical variation of parietal cells after vagotomy in cases of duodenal ulcer.

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Abstract
The influence of vagotomy on the gastric mucosa was elucidated histologically. Bioptical tissues were obtained from 10 control cases and from 26 cases of duodenal ulcer using an endoscope. Of the 26 cases of duodenal ulcer, 20 were subjected to truncal vagotomy with pyloroplasty and 6 to truncal vagotomy with hemigastrectomy. In the cases of duodenal ulcer, tissues were obtained at the preoperative stage and at 1, 3, 6 and 12 mo. on the time-course basis after the operation. The parietal cells were counted in a unit area (0.0176 mm2) between the middle and lower 1/3 part of the fundic gland in H.-E. hematoxylin-eosin stained paraffin sections under microscopy. The length of the fundic gland was also measured.