Synthesis and application in asymmetric C–C bond formation of solution phase ligand libraries of monodentate phosphoramidites
- 25 May 2004
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Organic & Biomolecular Chemistry
- Vol. 2 (12) , 1682-1684
- https://doi.org/10.1039/b404996a
Abstract
A library of 96 unique monodentate phosphoramidite ligands has been synthesized in solution and used in the asymmetric conjugate addition of potassium vinyltrifluoroborate to enones resulting in up to 88% ee.Keywords
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