Clinical Pharmacokinetics and Pharmacodynamics of Finasteride
- 1 January 1996
- journal article
- review article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 30 (1) , 16-27
- https://doi.org/10.2165/00003088-199630010-00002
Abstract
Finasteride is a potent 5α-reductase inhibitor that has shown limited success in men treated for benign prostatic hyperplasia (success is defined as a decrease in the symptoms associated with urinary...Keywords
This publication has 38 references indexed in Scilit:
- Picogram determination of finasteride in human plasma and semen by high-performance liquid chromatography with atmospheric-pressure chemical-ionization tandem mass spectrometryJournal of Chromatography B: Biomedical Sciences and Applications, 1994
- Three-year safety and efficacy data on the use of finasteride in the treatment of benign prostatic hyperplasiaUrology, 1994
- Effect of finasteride on serum PSA concentration in men with benign prostatic hyperplasia. Results from the North American phase III clinical trial.1993
- Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans.1992
- Scandinavian Clinical Study of Finasteride in the Treatment of Benign Prostatic HyperplasiaEuropean Urology, 1992
- High-performance liquid chromatographic method for the determination of finasteride in human plasma at therapeutic dosesJournal of Chromatography B: Biomedical Sciences and Applications, 1991
- Pharmacokinetics and biochemical efficacy after single and multiple oral administration of N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide, a new type of specific competitive inhibitor of testosterone 5α-reductase, in volunteersEuropean Journal of Drug Metabolism and Pharmacokinetics, 1991
- Effect of Finasteride, a 5α-Reductase Inhibitor on Prostate Tissue Androgens and Prostate-Specific Antigen*Journal of Clinical Endocrinology & Metabolism, 1990
- Hormonal effects of an orally active 4‐azasteroid inhibitor of 5α‐reductase in humansThe Prostate, 1989
- High-performance liquid chromatographic determination of N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide, a 4-azasteroid, in human plasma from a phase I studyJournal of Chromatography B: Biomedical Sciences and Applications, 1988