Characterization of the human natural killer (NK) cell in blood and lymphoid organs
- 15 January 1978
- journal article
- research article
- Published by Wiley in International Journal of Cancer
- Vol. 21 (1) , 42-50
- https://doi.org/10.1002/ijc.2910210109
Abstract
The human natural killer (NK) cell in peripheral blood is a non‐thymus‐dependent, (Fc+ C3−), Ig‐bearing lymphocyte and is probably identical to the human K cell, although not requiring the Fc receptor, in contrast to the K cell, for the lytic process. The human NK cell in tonsil and lymph node, on the other hand, is a non‐Ig‐ bearing T lymphocyte, lacking both Fc and C3 receptors.This publication has 21 references indexed in Scilit:
- Human natural cytotoxicity in the blood and lymphoid organs of healthy donors and patients with malignant diseaseInternational Journal of Cancer, 1978
- Comparison of the direct antiglobulin rosetting reaction with the mixed antiglobulin rosetting reaction for the detection of immunoglobulin on lymphocytesJournal of Immunological Methods, 1977
- Killer Cell (K) Activity in Human Normal Lymph Node, Regional Tumour Lymph Node and Inflammatory Lymph NodeInternational Archives of Allergy and Immunology, 1977
- Identification of a cell-surface antigen selectively expressed on the natural killer cell.The Journal of Experimental Medicine, 1977
- T and B Lymphocyte Populations in Human Normal Lymph Node, Regional Tumour Lymph Node and Inflammatory Lymph NodeInternational Archives of Allergy and Immunology, 1976
- Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cellsInternational Journal of Cancer, 1975
- Specificity of cell‐mediated cytotoxicity against human melanoma lines: Evidence for “non‐specific” killing by activated T‐cellsInternational Journal of Cancer, 1975
- Surface markers on human b and t lymphocytes. VI. Cytotoxicity against cell lines as a functional marker for lymphocyte subpopulationsInternational Journal of Cancer, 1975
- Cytotoxity of non‐T versus T‐lymphocytes from melanoma patients and healthy donors on short‐ and long‐term cultured melanoma cellsInternational Journal of Cancer, 1974
- Spontaneous antilymphoma reaction of preleukaemic AKR mice is a non-T-cell killingNature, 1974