Orally active cephalosporins and penicillins
- 1 April 1980
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 23 (4) , 405-412
- https://doi.org/10.1021/jm00178a011
Abstract
A number of orally active cephalosporins and penicillins with interesting biological activity were synthesized. Two of these, 7-[[[3,4-(methylenedioxy)phenyl]glycyl]amino]deacetoxycephalosporanic acid and 7-[[2-(2,3-dihydro-5-benzofuranyl)glycyl]amino]deacetoxycephalosporanic acid were considerably more active than cephalexin in vitro and in vivo against staphylococcal and streptococcal infections [in mice].This publication has 0 references indexed in Scilit: