THE ABSORPTION OF CYSTINE, METHIONINE AND CYSTEIC ACID FROM INTESTINAL LOOPS OF DOGS

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Abstract
The relative rates of absorption of l-cystine, dl-methionine and l-cysteic acid were measured in a dog with an isolated intestinal loop. Methionine appears to be absorbed about 3 times as rapidly as cystine, while cysteic acid is absorbed at a rate intermediate between the other 2. The amt. of the amino acid absorbed in a given time varies somewhat with the amt. placed in the loop: the larger the dose the more is absorbed. The amt. of the amino acid absorbed is the same, whether administered as the free ampholyte or as the Na salt. The amt. of the base absorbed is sufficiently specific and independent of the amino acid with which it is combined as to suggest that its absorption is an independent process. The ability of the animal used in these studies to absorb cystine and cysteic acid has been shown to have decreased to about J during a period of 2 years.

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