Rub1p Processing by Yuh1p Is Required for Wild-Type Levels of Rub1p Conjugation to Cdc53p
Open Access
- 1 June 2002
- journal article
- Published by American Society for Microbiology in Eukaryotic Cell
- Vol. 1 (3) , 491-494
- https://doi.org/10.1128/ec.1.3.491-494.2002
Abstract
In Saccharomyces cerevisiae , Rub1p, like ubiquitin, is conjugated to proteins. Before protein conjugation, the carboxyl-terminal asparagine residue of Rub1p is removed. Rub1p conjugation is dependent on the carboxyl-terminal processing enzyme Yuh1p, whereas Rub1p lacking the asparagine residue is conjugated without Yuh1p. Thus, Yuh1p is the major processing enzyme for Rub1p.Keywords
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