Vitamin K-dependent proteins and anticonvulsant medication
- 1 October 1983
- journal article
- research article
- Published by Wiley in Clinical Pharmacology & Therapeutics
- Vol. 34 (4) , 529-532
- https://doi.org/10.1038/clpt.1983.209
Abstract
Certain anticonvulsant drugs, especially phenytoin and phenobarbital, interfere with vitamin K metabolism as indicated by a raised serum osteocalcin level. This finding may be important in the pathogenesis of side effects of these medications.This publication has 6 references indexed in Scilit:
- Measurements of γ-carboxyglutamate and circulating osteocalcin in normal children and adultsClinica Chimica Acta; International Journal of Clinical Chemistry, 1983
- New biochemical marker for bone metabolism. Measurement by radioimmunoassay of bone GLA protein in the plasma of normal subjects and patients with bone disease.Journal of Clinical Investigation, 1980
- Phenytoin therapy and hemorrhagic diseaseThe Journal of Pediatrics, 1980
- Phenytoin, hemorrhage, skeletal defects and vitamin K in the newbornMedical Hypotheses, 1979
- Liver functions in children receiving carbamazepineThe Journal of Pediatrics, 1978
- Effect of Long‐term Vitamin D2 Treatment on Bone Morphometry and Biochemical Values in Anticonvulsant OsteomalaciaActa Medica Scandinavica, 1977