Highly efficient enzymatic resolution of homoallyl alcohols leading to a simple synthesis of optically pure fluoxetine and related compounds

This publication has 15 references indexed in Scilit:

• Lipase-catalysed resolution of 3-(aryloxy)-1,2-propanediol derivatives — Towards an improved active site model of Pseudomonas cepacia lipase (amano PS)
  Tetrahedron: Asymmetry, 1995
• Synthesis of R- and S- Fluoxetine, Norfluoxetine and Related Compounds from Styrene Oxide
  Synthetic Communications, 1995
• Efficient Asymmetric Hydrogenation of .BETA.- and .GAMMA.-Amino Ketone Derivatives Leading to Practical Synthesis of Fluoxetine and Eprozinol.
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1995
• Enzymic hydrolysis of ethyl 3-hydroxy-3-phenylpropanoate: observations on an enzyme active-site model
  The Journal of Organic Chemistry, 1992
• A new chemoenzymatic enantioselective synthesis of R-(−)-tomoxetine, (R)- and (S)-fluoxetine.
  Tetrahedron Letters, 1991
• A rule to predict which enantiomer of a secondary alcohol reacts faster in reactions catalyzed by cholesterol esterase, lipase from Pseudomonas cepacia, and lipase from Candida rugosa
  The Journal of Organic Chemistry, 1991
• Enantioselective and practical syntheses of R- and S-fluoxetines
  Tetrahedron Letters, 1989
• Asymmetric synthesis of both enantiomers of tomoxetine and fluoxetine. Selective reduction of 2,3-epoxycinnamyl alcohol with Red-Al
  The Journal of Organic Chemistry, 1988
• The absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitor
  Journal of Medicinal Chemistry, 1988
• Chiral synthesis via organoboranes. 18. Selective reductions. 43. Diisopinocampheylchloroborane as an excellent chiral reducing reagent for the synthesis of halo alcohols of high enantiomeric purity. A highly enantioselective synthesis of both optical isomers of Tomoxetine, Fluoxetine, and Nisoxetine
  The Journal of Organic Chemistry, 1988