Re: Fruit and Vegetable Intake and Risk of Major Chronic Disease

Abstract
Recently, Hung et al. ( 1 ) presented data on the associations between intake of fruits and vegetables and major chronic diseases based on two large American cohorts. They concluded that higher intake of fruits and vegetables might not be associated with a lower risk of cancer. This finding is at odds with a 1997 WHO/IARC report, which stated that an increased intake of fruits and vegetables is one of the most important lifestyle changes needed to reduce the high incidence of cancer in the Western world ( 2 ) . Consequently, we evaluated whether Hung et al.'s important findings could be reproduced in a different cohort study. In particular, we wanted to investigate the different associations among users and nonusers of dietary supplements shown by Hung et al.

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