Abstract
Significantly higher quantities of cholesteryl 14-methylhexadecanoate than of cholesteryl laurate and cholesteryl palmitate are bound by a homogeneous [rat] peptide-initiation factor and purified [rabbit] peptide-elongation factor 1. Cholesteryl 14-methylhexadecanoate may function as a specific allosteric modifier changing the conformation of protein-synthesis factors and thus modulating the activity of their binding sites.