Isoenzymes of membrane-bound β-glucosidase of human spleen
- 1 February 1980
- journal article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 185 (2) , 541-543
- https://doi.org/10.1042/bj1850541
Abstract
Normal human spleen contains two forms of membrane-bound beta-glucosidase, distinguishable by their thermostability and kinetic properties. The spleen from a patient with adult Gaucher's disease was deficient in the major, thermolabile, form of the enzyme.Keywords
This publication has 10 references indexed in Scilit:
- Synthesis and processing of protein-linked oligosaccharides in vivo.Journal of Biological Chemistry, 1979
- Activation of membrane-bound glucosylceramide: beta-glucosidase in fibroblasts cultured from normal and glucosylceramidotic human skin.Journal of Biological Chemistry, 1979
- Gaucher disease: isolation and comparison of normal and mutant glucocerebrosidase from human spleen tissue.Proceedings of the National Academy of Sciences, 1978
- Acid β-glucosidase and the diagnosis of Gaucher's disease in liver and spleenClinica Chimica Acta; International Journal of Clinical Chemistry, 1978
- Cell-specific differences in membrane β-glucosidase from normal and gaucher cellsBiochimica et Biophysica Acta (BBA) - Enzymology, 1977
- The diagnosis of gaucher's disease in liver using 4-methylumbelliferyl-β-d-glucopyranosideClinica Chimica Acta; International Journal of Clinical Chemistry, 1977
- Steroid β-D-glucosidase in steer liver and kidneyCanadian Journal of Biochemistry, 1977
- Solubilization of glucocerebrosidase from human placenta and demonstration of a phospholipid requirement for its catalytic activityBiochemical and Biophysical Research Communications, 1976
- Identity of ‘acid’ β-glucosidase and glucocerebrosidase in human spleenBiochemical Journal, 1973
- Metabolism of glucocerebrosides II. Evidence of an enzymatic deficiency in Gaucher's diseaseBiochemical and Biophysical Research Communications, 1965