The impact of total parenteral nutrition on liver function tests in patients with cancer
Open Access
- 15 March 1982
- Vol. 49 (6) , 1249-1257
- https://doi.org/10.1002/1097-0142(19820315)49:6<1249::aid-cncr2820490629>3.0.co;2-d
Abstract
In 143 patients undergoing 199 cycles of total parenteral nutrition (TPN), alkaline phosphatase (AP), serum glutamic‐oxaloacetic transaminase (SGOT), serum glutamic‐pyruvic transaminase (SGPT), direct bilirubin (DB), total bilirubin (TB), and lactic dehydrogenase (LDH) were measured and recorded before initiating TPN and weekly for seven weeks or until TPN was discontinued. Patterns of change were elevations and then plateaued. Direct bilirubin, TB and LDH showed no significant change. The patterns were independent of patient age, amount of fat emulsion administered, tumor burden, and nonprotein calorie to basal energy expenditure ratio.This publication has 23 references indexed in Scilit:
- Essential Fatty Acid Deficiency During Total Parenteral NutritionAnnals of Surgery, 1981
- Total Parenteral Nutrition in the Management of the Cancer PatientAnnual Review of Medicine, 1981
- Serum enzyme, bilirubin, uric acid, and cholesterol concentration changes during 7 days of total parenteral nutritionJournal of Parenteral and Enteral Nutrition, 1979
- Clinical and biological changes in liver function during intravenous hyperalimentationJournal of Parenteral and Enteral Nutrition, 1979
- High calorie infusion-induced hepatic impairments in infantsJournal of Parenteral and Enteral Nutrition, 1979
- Conjugated hyperbilirubinemia in infancy associated with parenteral alimentationThe Journal of Pediatrics, 1977
- Intrahepatic cholestasis with parenteral alimentationThe American Journal of Surgery, 1976
- Cholestasis in immature newborn infants: Is parenteral alimentation responsible?The Journal of Pediatrics, 1975
- Parenteral HyperalimentationAnnals of Surgery, 1972
- Hyperalimentation in cirrhotic patientsThe American Journal of Surgery, 1972