THE PRODUCTION OF EXPERIMENTAL POLYCYTHEMIA IN MAN BY THE DAILY ADMINISTRATION OF AMPHETAMINE SULFATE

1 August 1942

journal article
research article
Published by American Physiological Society in American Journal of Physiology-Legacy Content

Vol. 137 (1) , 94-96
https://doi.org/10.1152/ajplegacy.1942.137.1.94

Abstract

The daily oral adm. of amphetamine sulfate (10 mg.) caused a significant increase in the erythrocyte numbers of 5 of 6 normal human subjects within 6-12 days. The results are explained by assuming that amphetamine increases hemopoiesis by causing a local hypoxia of bone marrow through a diminution of the blood supply to this tissue.

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