DYNAMICS OF IGM-ANTIBODIES AND IGG-ANTIBODIES IN LEPTOSPIRAL INFECTION IN MAN

  • 1 January 1976
    • journal article
    • research article
    • Vol. 236  (2-3) , 336-343
Abstract
The dynamics of specific agglutinating antibodies belonging to different classes of immunoglobulins [Ig] in 1047 blood sera of 669 patients and persons who recovered from leptospirosis was studied. 19S and 7S antibodies were found in sera of patients with simultaneous presence of Leptospira pomona and L. grippotyphosa. The synthesis of specific leptospiral IgM and IgG antibodies correlated, but the concentration of the IgG was much lower. As a rule, IgM antibodies had a wide range of cross-reactions with leptospires of heterologous serogroups. However IgG-antibodies in 85% of cases reacted with homologous leptospires only.