Diabetic Renal-Retinal Syndrome

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Abstract
With predictive regularity, insulin-dependent diabetics, by about the 20th year of illness, manifest a syndrome of renal failure and vision loss. More than half of insulindependent diabetics die with uremia.1,3Retinopathy is present in 97% of uremic diabetics and accounts for impaired sight in 50%. The importance of the diabetic renal-retinal syndrome is underscored by data indicating that it accounts for one fourth of all patients beginning maintenance hemodialysis in Brooklyn, NY. Collaboration between nephrologist, transplant surgeon, and ophthalmologist has made possible the extension of useful life in an increasingly large subset of nephropathic diabetics. Recognition of the need for a team approach to treatment of the long-term diabetic will undoubtedly interdict blindness and facilitate rehabilitation for many. The natural history of glomerulosclerosis in early-onset diabetes has been clarified by Mogensen.4Although urinary tract infections, so-called glycogen nephrosis, and papillary necrosis all occur with a high attack rate

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