An Early Case Report of Muscular Dystrophy

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Abstract
Duchenne published his first case ofparaplégie hypertrophiquein 18611; by 1868 he had collected data on 13 cases ofparalysie musculaire pseudohypertrophique.2In the latter report, he reviewed the clinical course of the disease and its histology and described a novel technique for muscle biopsy to confirm the diagnosis prior to autopsy. The eponym "Duchenne's muscular dystrophy" reflects Duchenne's monumental contribution to the classification of disorders of muscle.3 An earlier case report by Dr Edward Meryon4has been credited as the first accurate and detailed description of muscular dystrophy.5.6Dr Meryon followed the initial case from 1848 to 1850 and described the family with four involved brothers in 1853. He attributed the disease to an interstitial fatty degeneration secondary to nutritional inadequacy. As a physician, William John Little (1810-1894) is remembered for his experimentation with intravenous solutions in the treatment of cholera. As an

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