The Ever-Continuing Search for Immunity in Tuberculosis
- 1 August 1952
- journal article
- research article
- Published by Taylor & Francis in Postgraduate Medicine
- Vol. 12 (2) , 101-117
- https://doi.org/10.1080/00325481.1952.11711238
Abstract
In this first section of a three part article, the author offers an historical sketch of early attempts to produce immunity against tuberculosis artificially. Live tubercle bacilli reduced in virulence, as well as those killed by various methods, were employed to produce immunity by numerous world renowned workers, including Koch, Von Behring and Calmette. A large number of such “immunizing agents” was developed. Calmette and Guérin used living tubercle bacillus isolated from a tuberculous cow in 1902. After reducing its virulence they named it Bacillus Calmette-Guéin (BCG) and strongly recommended its administration to both animals and humans.Keywords
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