Anticore Antibody Screening of Transfused Blood

Publisher Website
Google Scholar
Abstract
Aliquots of 130 HBsAg negative units of blood which were administered to 26 recipients were tested under code for anti-HBc by a solid phase radioimmunoassay technique. 14 of the 26 recipients developed posttransfusion hepatitis (PTH), including 6 cases of hepatitis B. Anti-HBc was detected in 7 or 5.3% of 130 donor units. Of the 14 patients acquiring PTH, 6 received a unit of anti-HBc-positive blood. Type B hepatitis occurred in 4 of the 7 anti-HBc recipients, and non-type B hepatitis in 2. Only 1 of 12 recipients who failed to develop PTH had received a unit containing anti-HBc.