Acute Hemolytic Anemia from Quinine Used as an Abortifacient

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Abstract
ACUTE hemolytic anemia following the administration of quinine has rarely been observed except in the presence of malaria. Terplan and Javert1 found 8 cases in the literature and reported a case of their own. All these patients were women who had taken or been given the drug as an abortifacient. All died. They showed evidence of a severe degree of intravascular hemolysis and, in most cases, hemoglobinuria. When measured, the nonprotein nitrogen content of the blood was found to be very high. The intake of the drug was not always beyond usual therapeutic dosage: as little as 0.4 gm. proved . . .

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