Cyanotic Malformations of the Heart with Pheochromocytoma

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Abstract
The clinical and pathologic features of five patients with pheochromocytoma associated with congenital cyanotic cardiac malformations have been described. This association appears to be more than mere coincidence. Chronic hypoxemia may be a significant factor in the development of this rare endocrine tumor in such patients. The finding of systemic hypertension combined with episodes of nervousness and sweating or repeated severe headaches initially aroused suspicion of a pheochromocytoma in the three patients in which this tumor was diagnosed clinically.

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