Liposomes and biotherapeutics
- 1 January 1991
- journal article
- Published by Springer Nature in Biotherapy
- Vol. 3 (1) , 25-42
- https://doi.org/10.1007/bf02175097
Abstract
Application of liposomes as delivery system for biotherapeutic peptides and proteins may offer important therapeutic advantages over existing delivery methods. Several approaches towards achieving improved delivery of biotherapeutics with liposomes are outlined. Although the literature on this topic is sporadic and frequently incomplete, enough of a research foundation exists to justify the conclusion that liposomes can play an important role in the formulation and delivery of biotherapeutics. However, it will be necessary to understand more fully the mechanisms of action before optimum liposomal dosage forms can be designed.Keywords
This publication has 59 references indexed in Scilit:
- Liposomes as carriers for polypeptidesAdvanced Drug Delivery Reviews, 1989
- Preparation of EGF labeled liposomes and their uptake by hepatocytesBiochemical and Biophysical Research Communications, 1989
- Liposomal Interferon- : Sustained Release Treatment of Simian Varicella Virus Infection in MonkeysThe Journal of Infectious Diseases, 1989
- Inhibition of interferon γ-induced macrophage microbicidal activity against Leishmania major by liposomes: Inhibition is dependent upon composition of phospholipid headgroups and fatty acidsInternational Journal of Immunopharmacology, 1989
- Some properties of tissue-type plasminogen activator reconstituted onto phospholipid and/or glycolipid vesiclesBiochemical and Biophysical Research Communications, 1987
- Growth induced by pulsatile infusion of an amidated fragment of human growth hormone releasing factor in normal and GHRF-deficient ratsNature, 1985
- Tumoricidal activity of human monocytes activated in vitro by free and liposome-encapsulated human lymphokines.Journal of Clinical Investigation, 1983
- Hormonal regulation of peptide receptors and target cell responsesNature, 1979
- Association of mouse interferon with liposomesFEBS Letters, 1977
- Application of drug-containing liposomes to the duration of the intramuscular absorption of water-soluble drugs in rats.CHEMICAL & PHARMACEUTICAL BULLETIN, 1975