Recurrent Urinary Tract Infections in Men
- 1 October 1979
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 91 (4) , 544-548
- https://doi.org/10.7326/0003-4819-91-4-544
Abstract
All men studied with recurrent urinary tract infections had a positive antibody-coated bacteria [ACB] test and 52% had evidence for prostate infection. Escherichia coli infection was present in 74% and urinary tract symptoms in 57% of those randomized. Thirty-eight patients were randomized in a double-blind clinical trial to receive 10 days of treatment with trimethoprim/sulfamethoxazole or a 12 wk course of the drug. Cure rate in patients receiving 12 wk of therapy (9 of 15) was higher than that in patients receiving a single 10-day course (3 of 15); the difference was marginally significant (P = 0.06). Recurrences were usually with the same organism and most (78%) occurred within 4 wk of discontinuing therapy. A standard 10-day therapy course usually fails to cure men with recurrent urinary tract infections with a positive ACB test.Keywords
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