Post-Transfusion Viral Hepatitis and the TTVS

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Abstract
From the mid-1940s until the 1960s, studies of post-transfusion viral hepatitis focused on prevention by immune serum globulin. The value of globulin in transfusion hepatitis is still to be determined.1 However, investigations of such prophylaxis provided an important source of information about the risk of post-transfusion hepatitis in the United States during that period. By the early 1970s, it was evident that a system of surveillance was needed for continued monitoring of the rate of post-transfusion disease. Recognition of the increased hazards associated with paid blood donors had led to a decreased use of commercial blood banks as a source . . .