S1P 3 ‐mediated Akt activation and crosstalk with platelet‐derived growth factor receptor (PDGFR)
Open Access
- 4 December 2003
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 18 (2) , 1-17
- https://doi.org/10.1096/fj.03-0302fje
Abstract
Akt plays a pivotal role in cell survival and tumorigenesis. We investigated the potential interaction between sphingosine-1-phosphate (S1P) and platelet-derived growth factor (PDGF) in the Akt signa...Keywords
Funding Information
- Charlotte Geyer Foundation
- National Institute of Mental Health
- National Institutes of Health (RO1 CA89228‐01A2)
This publication has 39 references indexed in Scilit:
- International Union of Pharmacology. XXXIV. Lysophospholipid Receptor NomenclaturePharmacological Reviews, 2002
- Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptorsBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
- Role of the Sphingosine 1-Phosphate Receptor EDG-1 in Vascular Smooth Muscle Cell Proliferation and MigrationCirculation Research, 2001
- Involvement of Phospholipase D in Sphingosine 1-Phosphate-induced Activation of Phosphatidylinositol 3-Kinase and Akt in Chinese Hamster Ovary Cells Overexpressing EDG3Published by Elsevier ,2001
- Lysophospholipid ReceptorsAnnual Review of Pharmacology and Toxicology, 2001
- Characterization of a Zebrafish (Danio rerio) Sphingosine 1-Phosphate Receptor Expressed in the Embryonic BrainBiochemical and Biophysical Research Communications, 2000
- Edg-1, the G protein–coupled receptor for sphingosine-1-phosphate, is essential for vascular maturationJournal of Clinical Investigation, 2000
- Functions of a new family of sphingosine-1-phosphate receptorsBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2000
- Vascular Endothelial Cell Adherens Junction Assembly and Morphogenesis Induced by Sphingosine-1-PhosphateCell, 1999
- Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1‐phosphateThe FASEB Journal, 1998