• 1 January 1965
    • journal article
    • research article
    • Vol. 32  (1) , 29-+
Abstract
The results of various controlled field trials carried out in British Guiana, Poland, the USSR and Yugoslavia were compared, and the effectiveness of the vaccines in man were evaluated. Acetone-inactivated typhoid vaccine, which has been established as an international reference preparation, has been proved in field trials to be of a high degree of effectiveness and to confer protection of long duration. Comparison of the results of the field trials with those of laboratory studies indicate that further research is needed in order to develop a test or tests the results of which can be fully correlated with the effectiveness of typhoid vaccines as demonstrated in man. Reference is also made to field studies of paratyphoid vaccines.